Prescription Rates for Antiplatelet Therapy (APT) in Coronary Artery Disease (CAD) - What Benchmark are We Aiming at
Bernd Hagen1, Reinhard Griebenow2
1Department of Evaluation and Quality Assurance, Central Institute for Statutory Health Care in Germany, Cologne/Berlin, Germany.
Insights
High prescription rates for antiplatelet therapy (APT) in coronary artery disease (CAD) patients were observed in a German Disease Management Program (DMP). Focusing on absolute numbers, not percentages, may further improve APT adherence in CAD care.
Area of Science:
- Cardiology
- Health Services Research
- Clinical Pharmacy
Background:
- Physicians strive to enhance patient health through improved clinical decision-making.
- Disease Management Programs (DMPs) aim to close performance gaps in patient care.
- Antiplatelet therapy (APT) is crucial for managing coronary artery disease (CAD).
Purpose of the Study:
- To analyze APT prescription rates in a large cohort of CAD patients within a German DMP.
- To evaluate the effectiveness of DMPs in achieving high APT attainment rates.
- To identify optimal methods for performance assessment in CAD management.
Main Methods:
- Retrospective analysis of 254,932 CAD patients from 3,405 practices in North Rhine, Germany (2019).
- Stratified analysis by sex and subgroups (myocardial infarction/acute coronary syndrome, PCI, bypass surgery).
- Calculation of APT prescription rates and missing prescription rates per practice and DMP visit.
Main Results:
- Overall APT prescription rates were 85.0% in males and 78.8% in females.
- Subgroup APT rates ranged from 87.8% to 92.8% across different patient categories.
- Missing APT prescription rates were very low, indicating high adherence within the DMP.
Conclusions:
- German DMPs demonstrate high attainment rates for APT in CAD patients.
- Expressing performance using absolute patient numbers may be more effective than percentages for improving adherence.
- Consideration of subgroup variations and evidence base is important for refining treatment recommendations.
Abstract:
Physicians always aim to improve their patients' health. CME should be designed not only to provide knowledge transfer, but also to influence clinical decision-making and to close performance gaps. In aretrospective study we analysed prescription rates for APT in 254,932 CAD patients (male: 64.4%), treated in atotal of 3,405 practices in 2019 in aDMP in the region of North Rhine, Germany. Analyses were run for the whole study population stratified by sex as well as for subgroups of patients suffering from myocardial infarction/acute coronary syndrome, or who have been treated with percutaneous coronary intervention or bypass surgery. Patients mean age was 72.7 ± 11.2 years (mean ± 1SD), mean duration of DMP participation was 7.2 ± 4.7 years, and mean cumulative number of DMP visits was 27 ± 17. APT prescription rates were 85.0% in male and 78.8% in female CAD patients. In subgroups of male CAD patients APT prescription rates were between 89.7% and 92.8%, in the same subgroups of female CAD patients the corresponding rates were between 87.8% and 92.0%. Rates for amissing APT prescription per practice were between .0044% and .0062% for male and female CAD patients, respectively. Rates for amissing APT prescription per practice and DMP visit were .0002% for both sexes. These results suggest that a DMP can achieve high attainment rates for APT in CAD. To further improve attainment rates, consideration of absolute numbers of eligible patients per practice or physician is probably more appropriate than expression of performance as percentage values. This is especially true if attainment rates show substantial variations between subgroups, if subgroups show substantial variation in size, if attainment rates are already in the magnitude of 80% or higher, and if there are disparities in the evidence base underlying treatment recommendations related to subgroups.
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