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Updated: Nov 29, 2025

Author Spotlight: Enhancing Vascular Function and Physical Capacity in Cardiovascular Disease Through Novel Interventions and NIRS Technology
Published on: March 22, 2024
Intracoronary near-infrared spectroscopy-role and clinical applications
Stephen E Wilkinson1, Ryan D Madder1
1Frederik Meijer Heart & Vascular Institute, Spectrum Health, Grand Rapids, MI, USA.
Abstract:
Intracoronary near-infrared spectroscopy (NIRS) has been developed and validated for the detection of lipid-rich plaque in the coronary arteries. A combined NIRS and intravascular ultrasound catheter is currently in clinical use and has an emerging role in evaluating plaques both before and after percutaneous coronary intervention. NIRS has recently been shown to positively identify both vulnerable patients and vulnerable plaques. This review focuses on the principles and image interpretation of intracoronary NIRS, as well as its clinical applications, limitations, and future directions.
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