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Updated: Nov 29, 2025

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Stabilization of U(III) to Oxidation and Hydrolysis by Encapsulation Using 2.2.2-Cryptand
Daniel N Huh1, Jeffrey M Barlow1, Sierra R Ciccone1
1Department of Chemistry, University of California, Irvine, California 92697, United States.
Abstract:
The electrochemical properties of U(III)-in-crypt (crypt = 2.2.2-cryptand) were examined in dimethylformamide (DMF) and acetonitrile (MeCN) to determine the oxidative stability offered by crypt as a ligand. Cyclic voltammetry revealed a U(III)/U(IV) irreversible oxidation at EPA= -0.49 V (vs Fe(C5H5)2+/0) in DMF and at EPA= -0.31 V (vs Fe(C5H5)2+/0) in MeCN. The electrochemistry of U(III)-in-crypt complexes in the presence of water was also examined. These studies are supported by crystallographically characterized examples of U(III)-in-crypt complexes as DMF, MeCN, and water adducts.
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