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Phototherapeutic keratectomy: Indications, methods and decision making
Rashmi Deshmukh1, Jagadesh C Reddy2, Christopher J Rapuano3
1Addenbrooke's Hospital, Cambridge University Hospitals, Cambridge, UK.
Indian Journal of Ophthalmology
|November 24, 2020
Summary
Phototherapeutic keratectomy (PTK) uses an excimer laser to treat anterior corneal lesions like erosions and scars. This minimally invasive procedure offers faster recovery and controlled ablation, making it a viable alternative to corneal transplantation.
Area of Science:
- Ophthalmology
- Corneal Surgery
Background:
- Anterior corneal pathologies require effective treatment options.
- Phototherapeutic keratectomy (PTK) is a superficial corneal ablation technique using an excimer laser.
Purpose of the Study:
- To discuss various techniques and outcomes of PTK.
- To highlight PTK as an alternative to keratoplasty for anterior corneal diseases.
Main Methods:
- Review of PTK techniques: large area, focal, and multifocal ablation.
- Discussion of adjunctive masking and antifibrotic agents (e.g., mitomycin C).
Main Results:
- PTK effectively treats conditions like recurrent corneal erosions, dystrophies, and scars.
- Adjunctive agents can improve outcomes and reduce complications like scarring and recurrence.
Conclusions:
- PTK offers a minimally invasive approach with controlled ablation depth and earlier recovery.
- It is a promising alternative to keratoplasty for specific anterior corneal pathologies.

