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Updated: Nov 28, 2025

A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Novel therapies for advanced skin carcinomas
Paulina Modrakowska1, Karolina Balik1, Małgorzata Maj1
1Department of Tissue Engineering, The Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.
Abstract:
Advanced skin carcinomas are a serious therapeutic problem. The statistical analysis shows a continuous increase in the incidence of both melanoma and non-melanoma skin cancers. Traditional therapies are characterized by low effectiveness and patients overall survival is not affected by them. By understanding the molecular pathways that lead to the neoplastic transformation and thanks to the knowledge of the immune system, it is possible to use personalized medicine in novel therapies for advanced skin carcinomas.
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