[Distribution of juvenile laryngeal papilloma in different stages]

Objective:To study the anatomical distribution and tumor extent of juvenile laryngeal papilloma（JLP）, and to sum up the similarity and difference in distribution between initiatial and recurrent tumor. Method:Data of 65 patients with JLP who were admitted to the Ear Institute, School of Medicine, Shanghai Jiao Tong University from January 2011 to December 2018 were retrospectively analyzed. The RRP tumor assessment method proposed by Derkay et al. was referred to, in which larynx was divided in to 11 anatomical sites. Result:2.9±1.3 Laryngeal anatomical sites were involved in patients with initial tumor, while that was 3.1±1.5 in patients with recurrent tumor. The most common sites were true vocal fords, anterior commissure and false vocal fords in both group; and the least ones were subglottis, posterior glottis and ary-epiglottic fold. However, subglottis（P=0.038） and trachea（P=0.007） were more likely to be involved in recurrent tumor, with statistical differences. Conclusion:There were differences in distribution of JLP between initial and recurrent tumor, which might be the result of suitable areas for HPV survival or micro-lesion of residual tumor.