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Updated: Aug 15, 2026

Flat Mount Imaging of Mouse Skin and Its Application to the Analysis of Hair Follicle Patterning and Sensory Axon Morphology
Published on: June 25, 2014
[Pili canaliculi, a form of uncombable hair]
1Universitäts-Hautklinik Hamburg.
Abstract:
Two further cases of the hair abnormality described in 1973 by Dupré et al. as "cheveux incoiffables" and later (1978) termed pili trianguli and canaliculi are reported. This hair abnormality--a distinct anomaly without the associated physical or mental abnormalities encountered in other cases of uncombable hair--starts in the first year of life, tending to improve or to become entirely normal with age. The morphological characteristics of such hairs are grooves along the hairshaft (demonstrable only by scanning electron microscopy), resulting in triangular, reniform, or irregular cross-sections. Of the various terms used to designate the condition, that proposed by Ferrando et al. (1980) pili canaliculi, appears to be the most appropriate.
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