Related Experiment Video
Updated: Nov 27, 2025

Multi-Modal Home Sleep Monitoring in Older Adults
Published on: January 26, 2019
[ARCHITECTONICS OF THE NIGHT SLEEP BASED ON ITS POLYSOMNOGRAPHIC CHARACTERISTICS IN PATIENTS WITH MULTIPLE SCLEROSIS]
N Voloshina1, V Vasylovskiy1, M Chernenko1
1State Institution "Institute of Neurology, Psychiatry and Narcology of the NAMS of Ukraine", Kharkiv; V. Karazin Kharkiv National University, Ukraine.
Abstract:
Aim of our study is to establish polysomnographic characteristics of nocturnal sleep in various forms of multiple sclerosis. Fifty eight patients with different clinical course of multiple sclerosis (MS) were included into the study. Disturbances of sleep architectonics were identified: representation of deep stages of NREM sleep, as well as REM sleep were reduced. Maintenance and continuity of sleep and its architecture were affected, leading to reduced sleep efficacy. Destabilization of sleep phases can be explained by activation of desynchronizing brain systems, leading to poor organization of NREM and REM sleep. These disorders were especially pronounced in patients with progressive course of MS. Thus, abovementioned sleep disorders can have prognostic value for predicting clinical course severity in patients with MS. Management of sleep disorders can improve quality of live in people with MS.
Related Concept Videos
Narcolepsy
Sleep-Wake Cycles
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
REM Sleep Behavior Disorder
RBD is significantly associated with...
Substance Use Disorders Affecting Sleep
Understanding the concepts of physical dependence,...
Management of Insomnia
Nightmares and Night Terrors
Nightmares...

