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Primary cutaneous blastic plasmacytoid dendritic cell neoplasm in a child: A challenging diagnosis and management
Marian Kristalia Rivas-Calderón1, Orly Cheirif-Wolosky1, Maria Eugenia Rosas-Romero2
1Dermatology Department, National Institute of Pediatrics, Mexico City, Mexico.
Abstract:
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive malignancy of the skin and hematopoietic system. There are few pediatric cases reported in the literature. Management of primary cutaneous BPDCN is challenging because, despite an apparently indolent clinical presentation, rapid dissemination with high mortality can occur. We describe a child with isolated cutaneous involvement who had a good response to chemotherapy as first-line treatment of BPDCN.