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Updated: Nov 27, 2025

Author Spotlight: Flow Cytometric Determination of Pyroptosis in Avian Cells
Published on: May 31, 2024
[Research progress of pyroptosis in respiratory diseases]
1Shandong Academy of Occupational Health and Occupational Medicine, Jinan 250062, China ; School of Public Health, Shandong First Medical University, Shandong Academy of Medical Sciences, Taian 271000, China.
Abstract:
Pyroptosis is a programmed death mode dependent on Caspase-1/4/5/11, which is caused by activation of inflammasome, accompanied by cell membrane rupture, pore formation and cell content release. As a new type of cell death, it is widely involved in respiratory diseases, such as pulmonary fibrosis, acute lung injury, bronchopulmonary dysplasia, chronic obstructive pulmonary disease and asthma. This article reviews the mechanism of pyroptosis and its role in different respiratory diseases, in order to provide new ideas for the treatment of respiratory diseases.
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