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Related Concept Videos

Cerebrum: Anatomical Overview I01:26

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The main and largest component of the human brain is the cerebrum. The cerebrum consists of two main parts: the cerebral cortex, an outer layer with wrinkles or folds known as gyri and shallow grooves called sulci, and a deeper region beneath it. The cerebrum divides into two distinct hemispheres and contains five different lobes: the frontal, parietal, temporal, occipital, and insula. The central sulcus separates the frontal and parietal lobes and two functionally important gyri — the...
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The diencephalon, etymologically translated as 'through brain,' plays an integral role as the conduit between the cerebrum and the vast extent of the nervous system. However, the olfactory system is an exception, as it interfaces directly with the cerebrum. The diencephalon, deeply ensconced beneath the cerebrum, primarily consists of three paired structures — the thalamus, hypothalamus, and epithelamus. It also includes accessory structures such as the subthalamus, which houses the...
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Cerebrum: Anatomical Overview II01:11

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Each cerebral hemisphere can be divided into three main regions. The outermost region, the cerebral cortex, is a thin layer (2 to 4 millimeters thick) made up of gray matter, consisting of neuron cell bodies, dendrites, glial cells, and blood vessels. The middle region, or white matter, is primarily composed of myelinated nerve fibers organized into three types of large tracts: association fibers, commissures, and projection fibers. Association fibers connect different areas within the same...
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The reticular formation is a complex network of gray and white matter located within the brainstem extending from the medulla to the midbrain.
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The brain is an integral component of the nervous system and serves as the center for processing sensory inputs, making decisions, and directing bodily actions. This complex organ is organized into three primary sections: the hindbrain, midbrain, and forebrain, each responsible for a range of vital functions.
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The brain is the most complex organ in the human body. It consists of four main parts: the cerebrum, diencephalon, cerebellum, and brainstem.
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Microdissection and Whole Mount Scanning Electron Microscopy Visualization of Mouse Choroid Plexus
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The claustrum.

Jared B Smith1, Albert K Lee2, Jesse Jackson3

  • 1Molecular Neurobiology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.

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|December 8, 2020
PubMed
Summary
This summary is machine-generated.

The claustrum, a brain region, has extensive connections to the cerebral cortex. This suggests its critical role in higher-order cognitive processes, including consciousness.

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Area of Science:

  • Neuroscience
  • Cognitive Neuroscience

Background:

  • The claustrum's function remains largely unknown despite over 200 years of investigation.
  • Interest in the claustrum was reignited by Crick and Koch's hypothesis linking it to consciousness.

Purpose of the Study:

  • To explore the function of the claustrum.
  • To investigate the claustrum's connectivity and physiological properties using modern neuroscience tools.

Main Methods:

  • Utilized modern systems neuroscience tools.
  • Leveraged advancements in genetic and viral technologies for brain region study.

Main Results:

  • Uncovered new information on the claustrum's anatomical connectivity.
  • Revealed physiological properties and functional aspects of the claustrum.
  • Established widespread, extensive connectivity between the claustrum and the entire cerebral cortex.

Conclusions:

  • The claustrum's extensive cortical connectivity supports its role in higher-order processes.
  • The findings align with and support the hypothesis of the claustrum's critical involvement in consciousness.