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Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography
Published on: February 18, 2022
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A practical guide to optical coherence tomography angiography interpretation
Eugenia Custo Greig1,2, Jay S Duker1, Nadia K Waheed3
1New England Eye Center, Tufts Medical Center, 800 Washington Street, Box 450, Boston, MA, 02111, USA.
International Journal of Retina and Vitreous
|December 9, 2020
Summary
Optical coherence tomography angiography (OCTA) is transitioning from research to clinical use. This review offers guidance on interpreting OCTA images for retinal conditions, enhancing clinical utility.
Area of Science:
- Ophthalmology
- Medical Imaging
- Retinal Vascular Imaging
Background:
- Optical coherence tomography angiography (OCTA) enables in vivo retinal vasculature imaging without contrast dye.
- While commercially available since 2014, OCTA has largely been confined to research, with increasing adoption in clinical settings.
- Few studies detail OCTA's clinical utility despite numerous publications on its use in studying retinal microvasculature.
Purpose of the Study:
- To provide an overview of OCTA imaging technology and interpretation.
- To discuss methods and best practices for preventing image acquisition artifacts.
- To outline the clinical utility of OCTA for various retinal pathologies.
Main Methods:
- Review of OCTA technology, including standard slab visualization.
- Discussion of artifact identification and prevention strategies.
- Analysis of OCTA's application in diagnosing retinal diseases like diabetic retinopathy and age-related macular degeneration.
Main Results:
- OCTA allows for individual visualization of each retinal plexus, a unique capability among retinovascular imaging modalities.
- The review details clinical applications for standard OCTA slabs.
- OCTA demonstrates significant potential for the clinical interpretation of retinal pathologies.
Conclusions:
- Optical coherence tomography angiography (OCTA) is evolving into a valuable clinical imaging device.
- This review serves as a toolkit for effective OCTA image interpretation in clinical practice.
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