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Hydroxyapatite Formation on Coated Titanium Implants Submerged in Simulated Body Fluid.
Tatiana Aviles1, Shu-Min Hsu1, Arthur Clark1
1Department of Restorative Dental Sciences, Division of Prosthodontics, College of Dentistry, University of Florida, Gainesville, FL 32610, USA.
Materials (Basel, Switzerland)
|December 11, 2020
Summary
This study investigated titanium implant coatings for dental prosthetics. Quaternized titanium nitride showed the most promising hydroxyapatite (HA) formation, crucial for osseointegration and implant success.
Area of Science:
- Biomaterials Science
- Dental Implantology
- Surface Chemistry
Background:
- Titanium implants are widely used in dentistry for prosthetics.
- Successful osseointegration, the binding of implants to bone, is critical for therapeutic outcomes.
- Hydroxyapatite (HA) formation on implant surfaces promotes osseointegration.
Purpose of the Study:
- To evaluate the efficacy of different implant surface coatings in promoting hydroxyapatite (HA) formation.
- To compare the HA-forming potential of titanium nitride (TiN), silicon dioxide (SiO2), and quaternized titanium nitride (QTiN) coatings.
Main Methods:
- Discs with various coatings (TiN, SiO2, QTiN) and controls were immersed in simulated body fluid (SBF) for 28 days.
- Simulated body fluid (SBF) was replenished every 48 hours.
- Hydroxyapatite (HA) layer formation was assessed via mass comparisons, scanning electron microscopy (SEM), and energy dispersive X-ray analysis (EDX).
Main Results:
- All tested coatings successfully developed a hydroxyapatite (HA) layer on the titanium implant surfaces.
- Quaternized titanium nitride (QTiN) demonstrated a superior yield of hydroxyapatite (HA) formation compared to other coatings.
- Scanning electron microscopy (SEM) and energy dispersive X-ray analysis (EDX) confirmed HA layer presence and composition.
Conclusions:
- The study confirms that various surface coatings can induce hydroxyapatite (HA) formation on titanium dental implants.
- Quaternized titanium nitride (QTiN) emerges as a promising coating for enhancing osseointegration.
- Further research is warranted to fully elucidate the potential of QTiN in dental implant applications.

