Skin Conductance and RR Interval for Regulated Discrete Physiological Stimuli: A Two Prong Strategy to Detect...

Background Several studies have found skin conductance a good indicator for detection of sympathetic response. But, valid and reliable tool for detection of sympathetic outflow in health and disease is still a quest. Thereby, comparison of superficial and, at core sympathetic effluence induced by deliberately supplied discrete external stimuli has been attempted in this study. Objective To assess the degree of sympathetic outflow for discrete cognitive and physical stimuli through perturbations in skin conductance and variations in heart rate in healthy adults. Method Quantitative and cross-sectional study was performed in 104 healthy subjects following random sampling method. Induction of sympathetic activity was realized by providing separate time bound cognitive exercises intervened with change in posture. Recordings to detect sympathetic responses at rest and, for supplied stimuli were made by electrocardiogram and galvanic skin response. Result Cognitive performance and postural change shifts baseline effluence and increases the sympathetic outflow significantly (p=0.000). There occurs no detectable rise in sympathetic effluence at the core (p=0.362) but, eventuate significantly appreciable sympathetic outflow to sweat glands in skin (p=0.000), when compared cognitive versus physical stimuli. Conclusion Sympathetic outflow induced by cognitive challenge and physical change in posture is readily assessable through sympathetic skin response yet core sympathetic effluence for latter stimuli is steady and unwavering. Differential effluence for sympathetic response called upon by discrete stimuli is operational for maintenance of steady state in healthy subjects.