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Published on: March 25, 2019
Polyoxometalate-Based Nanomaterials Toward Efficient Cancer Diagnosis and Therapy
Fei Lu1, Mengzhen Wang1, Na Li1
1College of Chemistry, Chemical Engineering and Materials Science, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Collaborative Innovation Center of Functionalized Probes for Chemical, Imaging in Universities of Shandong, Institute of Molecular and Nanoscience, Shandong Normal University, Jinan, 250014, P. R. China.
Abstract:
As an emerging class of inorganic metal oxides, organically functionalized polyoxometalates (POMs) or POM-based nanohybrids have been demonstrated promising potential for the inhibition of various cancer types by the virtue of their diversity in structures and significantly reduced toxicity. This contribution summarizes the latest achievement of POM-based nanomaterials in cancer diagnosis and various therapeutics to put forward our fundamental viewpoints on the design principles of modified POMs based on their application. In addition, major challenges and perspectives in this field are also discussed. We expect that this review will provide a valuable and systematic reference for the further development of POM-based nanomaterials.
