Naphthalenes A and B, two new naphthalene derivatives from the fungus Phellinus igniarius
Wei Liu1, Shihao Deng2, Yushuang Liu3
1Key Lab of Natural Product Chemistry and Application at Universities of Education Department of Xinjiang Uygur Autonomous Region, Yili Normal University, Yining, China.
Abstract:
Two new naphthalene derivatives, named naphthalene A (1) and naphthalene B (2), together with eight known compounds (3-10) were isolated from dichloromethane fraction of Phellinus igniarius. The structures of compounds were elucidated on the basis of spectroscopic analysis and absolute configurations were established based on electronic circular dichroism data. Compounds 9 and 10 exhibited moderate activity, increasing Glucose transporter 4 (GLUT-4) translocation by 1.62 and 1.87 folds, respectively.
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