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Photo-Based Nanomedicines Using Polymeric Systems in the Field of Cancer Imaging and Therapy
Patihul Husni1, Yuseon Shin1, Jae Chang Kim1
1Department of Global Innovative Drugs, College of Pharmacy, Chung-Ang University, 221 Heukseok dong, Dongjak-gu, Seoul 06974, Korea.
Biomedicines
|December 19, 2020
Summary
Photo-based nanomedicine leverages light-energy conversion for advanced optical imaging and phototherapy. This review explores photosensitive agents and nanotechnology systems for enhanced diagnostics and treatments.
Area of Science:
- Nanomedicine
- Biomedical Optics
- Phototherapy
Background:
- The application of photo-based nanomedicine in diagnostics and therapy is rapidly expanding.
- Light's energy conversion properties are utilized in optical imaging (OI) and phototherapy (PT).
- Nanotechnology offers solutions to existing challenges in OI and PT.
Purpose of the Study:
- To review common photosensitive agents (PSAs) for optical imaging and phototherapy.
- To discuss nanotechnology systems for photo-based diagnostics and therapies.
- To highlight the role of polymeric systems in photo-based nanomedicine.
Main Methods:
- Review of literature on photosensitive agents.
- Analysis of nanotechnology applications in phototherapy and optical imaging.
- Examination of polymeric systems in photo-based nanomedicine.
Main Results:
- Identified fluorescent and bioluminescent PSAs for OI/PT.
- Detailed agents for photodynamic therapy (PDT) and photothermal therapy (PTT).
- Described various polymeric nanotechnology systems for diagnostic and therapeutic uses.
Conclusions:
- Photo-based nanomedicine shows significant potential in diagnostics and therapy.
- Diverse PSAs and nanotechnology platforms are available for OI and PT.
- Polymeric systems are key components in developing advanced photo-based nanomedicine.
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