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Atomic Fluorescence Spectroscopy01:29

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Synthesis and Characterization of High c-axis ZnO Thin Film by Plasma Enhanced Chemical Vapor Deposition System and its UV Photodetector Application
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Optical fiber-based ZnS(Ag) detector for selectively detecting alpha particles.

Seiichi Yamamoto1, Ichio Aoki2, Tatsuya Higashi2

  • 1Department of Integrated Health Science, Nagoya University Graduate School of Medicine, Japan.

Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine
|December 22, 2020
PubMed
Summary

Researchers developed a novel optical fiber-based alpha particle detector using Silver-doped zinc sulfide (ZnS (Ag)). This detector selectively identifies alpha particles, showing higher sensitivity and pulse height than LYSO(Ce) detectors, while ignoring beta and gamma radiation.

Keywords:
Alpha particlesBeta particlesGamma photonsLYSOOptical fiberZnS(Ag)

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Area of Science:

  • Medical Physics
  • Nuclear Medicine
  • Instrumentation

Background:

  • Alpha radionuclide therapy requires precise detection of alpha particles for targeted treatment.
  • Existing detection methods may lack selectivity or sensitivity for in-vivo applications.
  • Optical fiber-based detectors offer potential for minimally invasive in-subject measurements.

Purpose of the Study:

  • To develop and evaluate an optical fiber-based alpha particle detector for potential use in alpha radionuclide therapy.
  • To compare the performance of a Silver-doped zinc sulfide (ZnS (Ag)) detector with a Lutetium-Yttrium Oxyorthosilicate doped with Cerium (LYSO(Ce)) detector.
  • To assess the detector's selectivity for alpha particles against beta and gamma radiation.

Main Methods:

  • Fabrication of an optical fiber detector with a ZnS(Ag) scintillation chamber at the fiber tip.
  • Construction of a comparative detector using a LYSO(Ce) scintillator inserted into the optical fiber.
  • Optical coupling of both detectors to a position-sensitive photomultiplier tube.
  • Analysis of two-dimensional distributions, energy spectra, and pulse shape spectra for alpha particles, beta particles, and gamma photons.

Main Results:

  • The ZnS(Ag) fiber detector exhibited approximately 5 times greater pulse heights and 2 times higher count rates for 5.5-MeV alpha particles compared to the LYSO(Ce) detector.
  • The ZnS(Ag) detector showed no counts for 2.28-MeV beta particles and 0.66-MeV gamma photons, demonstrating high selectivity.
  • The detector yielded minimal counts from natural alpha particles, confirming its specificity.

Conclusions:

  • The developed ZnS(Ag) optical fiber detector effectively and selectively detects alpha particles.
  • The detector is insensitive to beta and gamma radiation, making it suitable for alpha radionuclide therapy applications.
  • This technology presents a promising tool for direct alpha particle detection in subjects.