Dynamic motion analysis of impeller for the development of real-time flow rate estimations of a ventricular assist...

Implantable ventricular assist devices are used in heart failure therapy. These devices require real-time flow rate estimation for effective mechanical circulatory support. We previously developed a flow rate estimation method using the eccentric position of a magnetically levitated impeller to achieve real-time estimation. However, dynamic motion of the levitated impeller can compromise the method's performance. Therefore, in this study, we investigated the effects of dynamic motion of the levitated impeller on the time resolution and estimation accuracy of the proposed method. The magnetically levitated impeller was axially suspended and radially restricted by the passive stability in a centrifugal blood pump that we developed. The dynamic motions of impeller rotation and whirling were analyzed at various operating conditions to evaluate the reliability of estimation. The vibration response curves of the impeller revealed that the resonant rotational speed was 1300-1400 revolutions per minute (rpm). The blood pump was used as a ventricular assist device with rotational speed (over 1800 rpm) sufficiently higher than the resonant speed. The rotor-dynamic forces on the impeller (0.03-0.14 N) suppressed the whirling motion of the impeller, indicating that the dynamic motion could be stable. Although the temporal responsiveness should be determined based on the trade-offs among the estimation accuracy and time resolution, the real-time estimation capability of the proposed method was confirmed.