Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Optic nerve decompression in osteopetrosis.

O Al-Mefty1, J L Fox, N Al-Rodhan

  • 1Department of Neurosurgery, University of Mississippi Medical Center, Jackson.

Journal of Neurosurgery
|January 1, 1988
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Coriolis and centrifugal forces drive haltere deformations and influence spike timing.

Journal of the Royal Society, Interface·2019
Same author

Ondansetron Suppositories: Extemporaneous Preparation, Drug Release, Stability and Flux through Rabbit Rectal Membrane.

International journal of pharmaceutical compounding·2013
Same author

Stability of albuterol in continuous nebulization.

International journal of pharmaceutical compounding·2013
Same author

Naratriptan hydrochloride in extemporaneosly compounded oral suspensions.

International journal of pharmaceutical compounding·2013
Same author

Traffic accidents in Saudi Arabia: An epidemic.

Annals of Saudi medicine·2010
Same author

Lasing characteristics of new coumarin-analog dyes: broadband and narrow-1 inewidth performance.

Applied optics·2010
Same journal

Extent of resection as an independent predictor of survival for patients with glioblastoma as defined by the new WHO 2021 classification.

Journal of neurosurgery·2026
Same journal

Surgical treatment of schwannomas around the tarsal tunnel: a case series of 40 patients and systematic review of the literature.

Journal of neurosurgery·2026
Same journal

Direct targeting for focused ultrasound thalamotomy in the treatment of movement disorders.

Journal of neurosurgery·2026
Same journal

Development and internal validation of the Meningioma Functional Outcome Risk and Counseling Estimator 6 score, a point-based prognostic tool for predicting 6-week functional independence after intracranial meningioma resection.

Journal of neurosurgery·2026
Same journal

Connectional anatomy of the cerebellum: dentate nucleus and cerebellar peduncles from a surgical perspective.

Journal of neurosurgery·2026
Same journal

Press releases in neurosurgery: is scientific accuracy compromised in public reporting of neurosurgery research?

Journal of neurosurgery·2026
See all related articles

Osteopetrosis patients with vision loss improved after optic nerve decompression surgery. This microsurgical approach, involving wide decompression and orbital roof smoothing, showed positive results in most cases.

Area of Science:

  • Ophthalmology
  • Neurology
  • Genetics

Background:

  • Osteopetrosis is a rare genetic disorder causing increased bone density and modeling abnormalities.
  • Optic nerve atrophy and vision loss are common neurological findings, often attributed to optic canal compression.

Observation:

  • Recent studies suggest retinal degeneration may cause visual loss in osteopetrosis, questioning the efficacy of surgical decompression.
  • This study reports on six children with osteopetrosis and severe visual impairment.

Findings:

  • All six patients underwent bilateral microsurgical optic nerve decompression via supraorbital craniotomy.
  • Five patients experienced improved visual acuity post-surgery with no complications.
  • Key surgical techniques include wide optic nerve unroofing and drilling, plus orbital roof smoothing.

Related Experiment Videos

Implications:

  • Microsurgical optic nerve decompression appears effective for visual loss in pediatric osteopetrosis.
  • Refined surgical techniques enhance safety and efficacy, improving patient outcomes.
  • Further research is needed to fully elucidate the etiology of visual loss in osteopetrosis.