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Author Spotlight: Development of Simplified CRISPR-Based Tests for Rapid Detection of Infectious Diseases
Published on: August 16, 2024
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CRISPR: A new paradigm of theranostics
Neelam Yadav1, Jagriti Narang2, Anil Kumar Chhillar3
1Department of Biotechnology, Deenbandhu Chhotu Ram University of Science and Technology, Murthal, Sonepat; Centre for Biotechnology, Maharshi Dayanand University, Rohtak, Haryana.
Nanomedicine : Nanotechnology, Biology, and Medicine
|December 28, 2020
Summary
Clustered regularly interspaced short palindromic repeats (CRISPR) technology offers a sensitive and precise tool for diagnosing and treating infectious and hereditary diseases. This review explores CRISPR
Area of Science:
- Genomics
- Molecular Biology
- Biotechnology
Background:
- Infectious and hereditary diseases are leading causes of global mortality.
- Conventional diagnostic and therapeutic methods lack optimal sensitivity and specificity.
- Genome editing technologies are needed to address these limitations.
Purpose of the Study:
- To review the therapeutic and diagnostic applications of CRISPR technology.
- To explain the structure, mechanism, and theranostic potential of CRISPR tools.
- To highlight the role of CRISPR-integrated biosensing in disease diagnostics.
Main Methods:
- Review of existing literature on CRISPR technology applications.
- Explanation of CRISPR-Cas systems' structure and function.
- Discussion of CRISPR's role in theranostics and biosensing.
Main Results:
- CRISPR technology demonstrates high sensitivity, speed, and precision in pathogen detection.
- CRISPR facilitates understanding of cancer biology and hereditary disease mechanisms.
- CRISPR serves as a theranostic tool for diverse pathogens and genetic mutations.
Conclusions:
- CRISPR technology represents a significant advancement in treating and diagnosing infectious and hereditary diseases.
- CRISPR-based biosensing offers promising diagnostic capabilities.
- Further research into CRISPR applications can revolutionize healthcare for various diseases.
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