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Updated: Nov 23, 2025

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Systematic Assessment of Mammalian Skull Specimens for Dental and Temporomandibular Joint Pathology
Published on: August 22, 2022
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Three-dimensional mandibular dental changes with aging.
Daniela Garib1, Felicia Miranda2, Camila Massaro2
1Department of Orthodontics, Bauru Dental School, and Hospital for Rehabilitation of Craniofacial Anomalies, University of São Paulo, Bauru, São Paulo, Brazil.
Summary
Mandibular teeth showed slight 3D positional changes over 42 years, with eruption being the most consistent finding in untreated normal occlusion subjects.
Area of Science:
- Dentistry
- Orthodontics
- Human Anatomy
Background:
- Longitudinal evaluation of dental changes is crucial for understanding adult dentition.
- Digital models offer a precise method for tracking three-dimensional (3D) dental alterations over time.
Purpose of the Study:
- To assess 3D mandibular dental changes over 42 years in individuals with untreated normal occlusion.
- To analyze longitudinal alterations in tooth position from early to mature adulthood using digital models.
Main Methods:
- Utilized digital dental models from 8 untreated subjects (age 17 to 60).
- Registered models using 13 landmarks on the mucogingival junction.
- Measured 3D positional changes of teeth using SlicerCMF software.
Main Results:
- Significant 3D positional changes in mandibular teeth were observed.
- Consistent dental eruption of anterior and posterior teeth occurred.
- Slight mesial molar movement and lingual tipping of canines/premolars were noted.
Conclusions:
- Mandibular dental changes in untreated normal occlusion are minimal during adulthood.
- Tooth eruption is the primary change, with some mesial molar and lingual tipping tendencies.
- Digital model analysis provides insights into the aging process of the human mandible.
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