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Updated: Nov 22, 2025

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
Published on: May 17, 2024
Preoperative Octenidine Application in Breast Reconstruction Surgery.
Jens Hachenberg1, Ellen Acis2, Maximilian Mattes Auer-Schmidt3
1Department of Gynecology and Obstetrics, Hannover Medical School, Hannover, Germany; Hachenberg.Jens@mh-hannover.de.
Preoperative washing with Octenisan® may reduce infection in breast reconstruction, but this study found no significant difference in complication rates. Patient adherence was low, highlighting the need for better education in future trials.
Area of Science:
- Plastic Surgery
- Infectious Disease Prevention
Background:
- Postoperative infection is a significant concern in implant-based breast reconstruction.
- Preoperative use of disinfecting agents may lower infection rates.
Purpose of the Study:
- To evaluate the efficacy of preoperative Octenisan® wash lotion in reducing postoperative complications and infection rates in breast reconstructive surgery.
Main Methods:
- Retrospective analysis of 127 women undergoing implant-based breast reconstruction (2016-2019).
- Patients were instructed to use Octenisan® for five days preoperatively.
- Cohorts were divided based on adherence to the protocol (48.7% adherence).
Main Results:
- No significant difference in minor complication rates (34.4% vs. 36.6%) between Octenisan® users and non-users.
- No significant difference in major complication rates (7% vs. 5%) between groups.
- Low patient adherence (48.7%) was observed.
Conclusions:
- Octenisan® is safe for use in implant-based breast reconstructive surgery.
- The study did not demonstrate a significant reduction in complication or infection rates, likely due to small sample size and low adherence.
- Further larger studies are warranted to confirm efficacy, emphasizing patient education for protocol compliance.
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