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Scaling analyses for hyperpolarization transfer across a spin-diffusion barrier and into bulk solid media.

Nathan A Prisco¹, Arthur C Pinon², Lyndon Emsley²

¹Department of Chemical Engineering, University of California Santa Barbara, USA. bradc@ucsb.edu.

Physical Chemistry Chemical Physics : PCCP

|January 6, 2021

Summary

This study introduces a general approach to quantify hyperpolarization transfer rates between electron and nuclear spins. The findings offer new insights for optimizing hyperpolarization protocols like Dynamic Nuclear Polarization (DNP).

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Area of Science:

Physics
Physical Chemistry
Materials Science

Background:

Hyperpolarization techniques enhance nuclear spin sensitivity for applications in Magnetic Resonance Imaging (MRI) and spectroscopy.
Understanding spin polarization transfer is crucial for optimizing hyperpolarization protocols, but current models often lack quantitative predictive power.

Purpose of the Study:

To develop a general theoretical framework for determining hyperpolarization transfer rates between electron and nuclear spins.
To establish quantitative relationships for predicting and optimizing hyperpolarization protocols, including Dynamic Nuclear Polarization (DNP).

Main Methods:

Analogy to heat and mass transfer film theory to model polarization transfer.
Empirical measurement of a DNP polarization-transfer coefficient as a function of bulk matrix 1H spin density.
Derivation of dimensional property relationships to analyze spin polarization dynamics.

Main Results:

Identified two distinct kinetic regimes governing polarization transfer, linked to different rate-limiting phenomena.
Quantitative analyses closely match experimental data for hyperpolarization accumulation, propagation, and dissipation in solids.
Provided evidence for kinetically-limited transfer due to a spin-diffusion barrier.

Conclusions:

The developed classical approach provides general design criteria for analyzing and optimizing polarization transfer processes.
Applicable to complex interfaces and composite media in materials science, physical chemistry, and nuclear spintronics.
Offers a quantitative method to improve the effectiveness of hyperpolarization protocols like DNP.