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Updated: Nov 22, 2025
Transport Properties of Ibuprofen Encapsulated in Cyclodextrin Nanosponge Hydrogels: A Proton HR-MAS NMR Spectroscopy Study
Published on: August 15, 2016
Rapid synthesis of multifunctional β-cyclodextrin nanospheres as alkali-responsive nanocarriers and selective
Qiuju Li1, Dandan Wang1, Xian Fang1
1Biomedical Multidisciplinary Innovation Research Institute, Shanghai East Hospital, State Key Laboratory of Pollution Control and Resource Reuse, College of Environmental Science and Engineering, Tongji University, 1239 Siping Road, Shanghai 200092, China. shunmao@tongji.edu.cn and Shanghai Institute of Pollution Control and Ecological Security, Shanghai 200092, China.
Abstract:
Novel hypercross-linked β-cyclodextrin nanospheres are rapidly synthesized with 4-amino-6-hydroxy-2-mercaptopyrimidine as a cross-linker within 5 min at a low temperature of 60 °C in the open water phase, thereby radically simplifying and accelerating the conventional time-consuming and environmentally harsh synthesis of cyclodextrin-containing polymers. The nanospheres demonstrate excellent and controllable performance as alkali-responsive nanocarriers and selective adsorbents for antibiotics.
