Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Insufficient Sleep and Sleep Deprivation01:13

Insufficient Sleep and Sleep Deprivation

652
Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...
652
Substance Use Disorders Affecting Sleep01:24

Substance Use Disorders Affecting Sleep

278
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
278
Understanding Sleep01:11

Understanding Sleep

1.2K
Sleep, an essential biological state, involves significant reductions in physical activity, sensory awareness, and interaction with the environment. This complex physiological process is primarily regulated by specific brain regions, notably the hypothalamus and pons, which govern the sleep-wake cycle or circadian rhythm.
The circadian rhythm, a nearly 24-hour cycle, is deeply influenced by environmental light cues. Light exposure directly affects the hypothalamus, which in turn regulates...
1.2K
Sleep-Wake Cycles01:24

Sleep-Wake Cycles

2.4K
Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and  rapid eye movement (REM).
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
2.4K
Accessory Structures of the Eye01:17

Accessory Structures of the Eye

2.8K
Optical perception, or vision, is an extraordinary sense dependent on converting light signals received via the ocular organs. These organs, known as eyes, are securely positioned within the bony cavities of the skull, called orbits. The orbits serve a dual purpose: a protective shield for the ocular globes and a stable attachment point for the soft ocular tissues. The eye's external protective mechanisms include the eyelids, which are edged with lashes that act as a barrier against foreign...
2.8K
Stages of Sleep01:22

Stages of Sleep

1.1K
Sleep progresses through distinct stages, each characterized by specific brain wave patterns and physiological responses ranging from wakefulness to stages of non-rapid eye movement, known as non-REM, to rapid eye movement, referred to as REM. Understanding these stages helps in recognizing how sleep supports various bodily and cognitive functions.
Before sleep begins, in wakefulness, the brain exhibits primarily beta waves, which are high in frequency and low in amplitude, indicating alertness...
1.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Editorial: Neuropsychological mechanisms underlying risk, resilience, and intervention response in youth substance use.

Frontiers in psychology·2026
Same author

Genome-wide discovery reveals 30 loci for choroidal thickness and uncovers potential causal links with angle-closure glaucoma.

medRxiv : the preprint server for health sciences·2026
Same author

Deviation in development of dorsal association tracts during preadolescence links to concurrent and future cognitive performance and transdiagnostic psychopathology.

Nature communications·2026
Same author

Uncovering the Genetic Architecture of Optic Nerve Integrity Estimates through Genome-wide Association Study Meta-analyses.

medRxiv : the preprint server for health sciences·2026
Same author

Associations between Ocular Surface Microbiome and Refractive Status in Children and Adolescents.

Ophthalmology science·2026
Same author

Mindfulness-Based Interventions for Adolescent Substance Use and Substance Use Disorders: A Systematic Review.

Pediatrics·2026

Related Experiment Video

Updated: Nov 22, 2025

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression
04:33

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression

Published on: April 26, 2024

997

The relationship between dry eye and sleep quality.

Morten Schjerven Magno1, Tor Paaske Utheim2, Harold Snieder3

  • 1Department of Plastic and Reconstructive Surgery, Oslo University Hospital, Oslo, Norway; Departments of Ophthalmology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, Postbus 30.001, Groningen, the Netherlands.

The Ocular Surface
|January 9, 2021
PubMed
Summary

Dry eye significantly impacts sleep quality, with over a third of dry eye patients experiencing poor sleep. This association persists even after accounting for other health conditions, highlighting dry eye

Keywords:
DEDDry eyeLifelinesPSQISleepWHS dry Eye questionnaire

More Related Videos

Clinical Application of Intense Pulsed Light Therapy and Radio Frequency for Treatment of Ocular Surface Diseases
07:36

Clinical Application of Intense Pulsed Light Therapy and Radio Frequency for Treatment of Ocular Surface Diseases

Published on: July 3, 2025

406
Comparing Objective Conjunctival Hyperemia Grading and the Ocular Surface Disease Index Score in Dry Eye Syndrome During COVID-19
06:29

Comparing Objective Conjunctival Hyperemia Grading and the Ocular Surface Disease Index Score in Dry Eye Syndrome During COVID-19

Published on: May 25, 2022

2.6K

Related Experiment Videos

Last Updated: Nov 22, 2025

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression
04:33

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression

Published on: April 26, 2024

997
Clinical Application of Intense Pulsed Light Therapy and Radio Frequency for Treatment of Ocular Surface Diseases
07:36

Clinical Application of Intense Pulsed Light Therapy and Radio Frequency for Treatment of Ocular Surface Diseases

Published on: July 3, 2025

406
Comparing Objective Conjunctival Hyperemia Grading and the Ocular Surface Disease Index Score in Dry Eye Syndrome During COVID-19
06:29

Comparing Objective Conjunctival Hyperemia Grading and the Ocular Surface Disease Index Score in Dry Eye Syndrome During COVID-19

Published on: May 25, 2022

2.6K

Area of Science:

  • Ophthalmology
  • Sleep Medicine
  • Public Health

Background:

  • Sleep quality is crucial for overall health and well-being.
  • Dry eye disease is a prevalent condition affecting millions globally.
  • The relationship between dry eye and sleep disturbances requires further investigation.

Purpose of the Study:

  • To investigate the association between dry eye disease and sleep quality.
  • To analyze this relationship in a large, population-based cohort.
  • To identify potential confounding factors influencing the association.

Main Methods:

  • Utilized data from 71,761 participants in the Lifelines cohort.
  • Assessed dry eye using the Women's Health Study Dry Eye Questionnaire.
  • Evaluated sleep quality with the Pittsburgh Sleep Quality Index (PSQI) and employed logistic regression analysis, adjusting for numerous covariates.

Main Results:

  • 8.9% of participants had dry eye, with 36.4% experiencing poor sleep quality compared to 24.8% of controls.
  • Dry eye remained significantly associated with poor sleep (OR 1.20) after adjusting for comorbidities.
  • All sleep quality components were worse in dry eye patients, with symptom frequency correlating with sleep quality decline.

Conclusions:

  • Dry eye disease is strongly linked to diminished sleep quality across diverse demographics.
  • The impact of dry eye on sleep is substantial, particularly for individuals with frequent symptoms.
  • These findings underscore the importance of addressing dry eye to improve patient quality of life.