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Updated: Nov 21, 2025

In Silico Clinical Trials for Cardiovascular Disease
Published on: May 27, 2022
Efficiency of semi-implicit alternating direction implicit methods for solving cardiac monodomain model
Youssef Belhamadia1, Zeinab Rammal1
1American University of Sharjah, Department of Mathematics, Sharjah, United Arab Emirates.
Abstract:
It is well known that numerical simulations of the cardiac monodomain model require fine mesh resolution, which increases the computational resources required. In this paper, we construct three operator-splitting alternating direction implicit (ADI) schemes to efficiently solve the nonlinear cardiac monodomain model. The main objective of the proposed methods is to reduce the computational time and memory consumed for solving electrocardiology models, compared to standard numerical methods. The proposed methods have second-order accuracy in both space and time while evaluating the ionic model only once per time-step. Several examples using regular wave, spiral wave reentry, and nonsymmetrical scroll wave are conducted, and the efficiency of the proposed ADI methods is compared to the standard semi-implicit Crank-Nicolson/Adams-Bashforth method. Large-scale two- and three-dimensional simulations are performed.
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