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[APITHERAPY - THE GOOD AND THE MYTH].

Daphna Katz-Talmor^1,2, Yehuda Shoenfeld^2,3

¹Department of Medicine 'A', University Hospital Samason Assuta Ashdod, Israel.

|January 21, 2021

Summary

Apitherapy, using bee venom for health, is gaining interest. Its anti-inflammatory peptides like Melittin show therapeutic potential, but allergies and anaphylaxis require caution.

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Area of Science:

Alternative Medicine
Biochemistry

Background:

Apitherapy, the use of bee venom for medical conditions, has ancient roots.
Recent Google search trends show a significant increase in public interest in apitherapy over the last decade.
Controlled studies suggest potential beneficial effects of bee venom therapy.

Purpose of the Study:

To explore the therapeutic potential of bee venom.
To highlight the anti-inflammatory components within bee venom.
To acknowledge the need for safety considerations in apitherapy.

Main Methods:

Analysis of Google search trends to gauge public interest in apitherapy.
Review of existing controlled studies on bee venom's efficacy.
Identification of key anti-inflammatory peptides in bee venom, such as Melittin and Apamin.

Main Results:

A notable rise in online searches for apitherapy indicates growing public interest.
Evidence from controlled studies supports the beneficial effects of bee venom.
Bee venom contains several peptides with anti-inflammatory properties, including Melittin and Apamin.

Conclusions:

Bee venom possesses anti-inflammatory properties with therapeutic promise.
Synthetic approaches are being explored to harness these therapeutic peptides.
Careful consideration of bee venom allergy and anaphylaxis risk is crucial for safe application.