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Related Concept Videos

Ultrasound II: Endoscopic Ultrasound and FibroScan01:25

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Endoscopic Ultrasound (EUS) and FibroScan are valuable diagnostic tools in gastroenterology and hepatology, each with specific applications and techniques.
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The abdominal examination is a cornerstone of clinical medicine, serving as a critical tool in diagnosing various gastrointestinal (GI) diseases. It involves a systematic approach that includes inspection and auscultation, each with distinct yet complementary roles in assessing the abdomen. This article will delve into these two primary methods healthcare professionals use to examine the abdomen.
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Imaging Studies IV: Magnetic Resonance Imaging01:27

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Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...
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Ultrasound I: Abdominal Ultrasonography01:20

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Introduction:
Abdominal ultrasonography, commonly known as abdominal ultrasound, is a vital, non-invasive medical imaging technique widely used in healthcare.
Procedure:
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Assessment of the Abdomen II: Percussion01:18

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Percussion is a fundamental technique used to assess the liver, spleen, and abdominal organs by tapping the abdomen and interpreting the resulting sounds. This method helps identify fluid, distention, and masses through variations in sound, such as the high-pitched tympany of air-filled areas and the dullness of solid masses. Understanding how to percuss these organs provides valuable information for healthcare professionals in diagnosing conditions early.
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Assessment of the Abdomen III: Palpation01:23

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Palpation is a crucial tactile examination method for assessing abdominal organs and detecting conditions like tenderness, distention, masses, or fluid. It involves both light and deep palpation techniques, each serving specific diagnostic purposes. Light palpation helps identify tenderness and other surface-level indicators, while deep palpation locates and assess abdominal masses and organ boundaries. A skilled professional can gather valuable insights through palpation, including evaluating...
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Magnetic Resonance Elastography Methodology for the Evaluation of Tissue Engineered Construct Growth
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MR Elastography of the Abdomen: Basic Concepts.

Suraj D Serai1, Meng Yin2

  • 1Department of Radiology, Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA, USA. serais@email.chop.edu.

Methods in Molecular Biology (Clifton, N.J.)
|January 21, 2021
PubMed
Summary
This summary is machine-generated.

Magnetic resonance elastography (MRE) noninvasively assesses tissue stiffness, a fibrosis marker. This technique, primarily used for liver fibrosis, shows promise for other organs like the kidney.

Keywords:
FibrosisKidneyMRIMagnetic resonance elastography (MRE)Preclinical imagingStiffness

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Area of Science:

  • Biomedical Imaging
  • Medical Physics
  • Biomaterials

Background:

  • Magnetic resonance elastography (MRE) is an advanced imaging technique that quantifies tissue elasticity.
  • Tissue stiffness, measured by shear modulus, serves as a surrogate marker for fibrosis.
  • MRE has demonstrated efficacy in differentiating fibrosis stages, particularly in the liver.

Purpose of the Study:

  • To introduce the fundamental concepts of Magnetic Resonance Elastography (MRE).
  • To highlight emerging and novel applications of MRE beyond its traditional use in liver fibrosis assessment.
  • To discuss the potential of MRE in evaluating organ fibrosis and disease progression.

Main Methods:

  • MRE involves applying mechanical vibrations to tissues.
  • Internal tissue displacements are measured using magnetic resonance phase encoding.
  • Mechanical properties are inferred from displacement data to create elastograms.

Main Results:

  • MRE accurately distinguishes between absent/low and high stages of fibrosis, especially in the liver.
  • Emerging applications show MRE's potential in assessing fibrosis in the brain, kidney, pancreas, spleen, and heart.
  • Recent studies highlight MRE's promise for noninvasive renal fibrosis evaluation in chronic kidney disease patients.

Conclusions:

  • MRE is a versatile, noninvasive imaging modality for assessing tissue stiffness and fibrosis.
  • Its application is expanding beyond the liver to various organs, offering significant diagnostic potential.
  • Further development and validation in preclinical models are crucial for broader clinical adoption.