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Effect of continuous illumination on secretion of pregnane compounds by the rat ovary
T Kosaka1, T Sawada, S Ichikawa
1Department of Animal Reproduction, College of Agriculture, University of Osaka Prefecture, Japan.
Experientia
|January 15, 1988
Abstract:
Differences in the secretion of pregnane compounds from rats with follicular polycystic ovaries under constant light and with normal preovulatory ovaries under light-dark conditions were compared. The injection of LH greatly increased the secretion of progesterone. 5 alpha-pregnane-3,20-dione and 3 alpha-hydroxy-5 alpha-pregnan-20-one, in both types of ovaries, but the response of the two progesterone metabolites in the polycystic ovaries was low, suggesting low 5 alpha-reductase activity.