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Is COVID-19 lockdown associated with vitamin D deficiency?
Giuseppe Lippi1,2, Anna Ferrari2, Giovanni Targher3
1Section of Clinical Biochemistry, University of Verona, Verona, Italy.
Insights
Vitamin D levels in Italian outpatients did not significantly change during the COVID-19 pandemic. Vitamin D deficiency prevalence also marginally decreased, suggesting no increase during lockdown periods.
Area of Science:
- Endocrinology
- Public Health
Background:
- Vitamin D is crucial for bone health and immune function.
- The COVID-19 pandemic and associated lockdowns raised concerns about potential impacts on vitamin D levels due to reduced sun exposure.
Purpose of the Study:
- To evaluate the impact of the COVID-19 lockdown on serum vitamin D concentrations and deficiency prevalence in adult outpatients.
- To determine if vitamin D deficiency increased during the COVID-19 outbreak in Italy.
Main Methods:
- Retrospective review of vitamin D tests for outpatients aged 18 years and older.
- Comparison of serum vitamin D levels and deficiency rates from the 2 years preceding the lockdown to the period following the lockdown.
Main Results:
- Serum vitamin D concentrations showed no significant difference between the pre-lockdown and post-lockdown periods (78 vs. 77 nmol/l).
- The prevalence of vitamin D deficiency was marginally lower in 2020 compared to previous years (16.0% vs. 17.9%).
Conclusions:
- The COVID-19 lockdown and outbreak did not lead to an increase in vitamin D deficiency among adult outpatients in the studied Italian province.
- These findings suggest that public health measures did not negatively impact vitamin D status in this population.
Abstract:
All vitamin D tests carried out for outpatients aged 18 years or older during the last 3 years at an Italian University Hospital was reviewed. The serum vitamin D concentrations measured since the Italian coronavirus diseases 2019 (COVID-19) lockdown to present did not significantly differ from the previous 2 years (78 vs. 77 nmol/l; P = 0.277), whilst the prevalence of vitamin D deficiency was found to be even marginally lower in 2020 (16.0% vs. 17.9%; P = 0.003). These results suggest that vitamin D deficiency in our province has not increased during the Italian COVID-19 outbreak or in correspondence with the nationwide lockdown.
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