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Prosthetic Finger Joint Infection Due to Aspergillus terreus

Takaaki Kobayashi1, Ericka Lawler2, Hasan Samra3

  • 1Division of Infectious Diseases, Department of Internal Medicine, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.

Open Forum Infectious Diseases
|January 29, 2021
PubMed

Insights

Fungal periprosthetic joint infections (PJIs) are rare but serious. This case highlights successful treatment of a finger PJI caused by Aspergillus terreus in an immunocompetent patient.

Area of Science:

  • Mycology
  • Infectious Diseases
  • Orthopedic Surgery

Background:

  • Fungal periprosthetic joint infections (PJIs) are uncommon but carry a high mortality risk.
  • Early and accurate diagnosis is crucial for effective management of PJIs.
  • Aspergillus species are increasingly recognized as potential pathogens in opportunistic infections.

Observation:

  • A case of finger periprosthetic joint infection (PJI) caused by Aspergillus terreus is presented.
  • The patient was immunocompetent and had a history of soil exposure.
  • The infection occurred in a prosthetic joint of the finger.

Findings:

  • Surgical debridement combined with voriconazole treatment led to a successful outcome.
  • Identification of Aspergillus terreus is critical due to its inherent resistance to amphotericin B.
  • This highlights the importance of species-specific antifungal susceptibility testing.

Implications:

  • This case underscores the need for considering fungal etiologies in PJIs, even in immunocompetent individuals.
  • Voriconazole can be an effective treatment option for Aspergillus-related PJIs.
  • Clinicians should be aware of the variable antifungal resistance patterns in Aspergillus species affecting prosthetic joints.
Keywords:
Aspergillus terreusfungal prosthetic joint infection

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