Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pharynx01:20

Pharynx

4.3K
The pharynx, a tubular structure framed by skeletal muscle and lined with mucous membrane, extends continuously from the nasal cavities. It is segmented into three major areas: the nasopharynx, oropharynx, and laryngopharynx.
Nasopharynx
The nasopharynx, bordered by the conchae of the nasal cavity, serves exclusively as an air conduit. In its superior region, the pharyngeal tonsils or adenoids are located. These tonsils are clusters of lymphoid reticular tissue akin to a lymph node. The precise...
4.3K
Nose and Nasal Cavity01:24

Nose and Nasal Cavity

7.4K
The nose is composed of an observable exterior segment (external nose) and an internal segment within the skull known as the nasal cavity (internal nose). The external nose, visible on the face, consists of a framework of bone and hyaline cartilage enveloped in skin and muscle and lined with a mucous membrane. This structure is supported by the frontal bone, nasal bones, and maxillary bone and is supplemented by a cartilaginous framework comprising the septal nasal cartilage, lateral nasal...
7.4K
Chronic Pharyngitis01:23

Chronic Pharyngitis

8.1K
Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
8.1K
Suctioning the Nasopharyngeal Airway01:29

Suctioning the Nasopharyngeal Airway

1.8K
Nasopharyngeal suctioning is a procedure to remove secretions from the upper part of the respiratory tract that the patient cannot clear independently. It helps maintain airway patency and prevents complications such as aspiration pneumonia.
Equipment Required
1.8K
Anatomy of Respiratory System I: Upper Respiratory Tract01:29

Anatomy of Respiratory System I: Upper Respiratory Tract

3.6K
The upper respiratory tract plays a vital role in the respiratory system, comprising several structures that facilitate air intake and prepare air for the lungs. It also serves as the first line of defense against pathogens and particles. This tract includes the nose and nasal cavity, the oral cavity, the paranasal sinuses, and the pharynx, each with specific functions and features.
Nose and nasal cavity
The nose and nasal cavity represent the main external openings of the respiratory tract....
3.6K
Acute Pharyngitis01:30

Acute Pharyngitis

2.6K
Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
2.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Carriage epidemiology of Moraxella catarrhalis in an all-age community cohort between 2016 and 2018.

Access microbiology·2026
Same author

Of Commensals and Opportunists: Genomics of Coagulase-Negative Staphylococci During Sequential Ear and Eye Infections in a Healthy Adult.

MicrobiologyOpen·2026
Same author

Dynamics of a large multidrug-resistant plasmid encoding New Delhi metallo-β-lactamase-1 and oxacillinase-58 carbapenemases in <i>Acinetobacter baumannii</i> clinical isolates from a tertiary hospital in Malaysia.

Microbial genomics·2026
Same author

Prevalence of pneumococcal carriage and risk factors for pneumonia and carriage among under-5 children in Malaysia: findings from the MY-Pneumo study.

Pneumonia (Nathan Qld.)·2025
Same author

The Road Less Traveled: Exploring the Genomic Characteristics and Antimicrobial Resistance Potential of Acinetobacter baumannii From the Indigenous Orang Asli Community in Peninsular Malaysia.

MicrobiologyOpen·2025
Same author

From bedside to bug side: clinical, haematological and genetic markers of antibiotic-resistant bacterial isolates from children admitted with sepsis in Kaduna State, Nigeria - a protocol for a cross-sectional study.

BMJ open·2025

Related Experiment Video

Updated: Nov 19, 2025

Assessing the Viability of a Synthetic Bacterial Consortium on the In Vitro Gut Host-microbe Interface
10:24

Assessing the Viability of a Synthetic Bacterial Consortium on the In Vitro Gut Host-microbe Interface

Published on: July 4, 2018

12.0K

The nasopharyngeal microbiome.

David W Cleary1,2, Stuart C Clarke1,2,3

  • 1Faculty of Medicine and Institute for Life Sciences, University of Southampton, Southampton SO17 1BJ, U.K.

Emerging Topics in Life Sciences
|February 2, 2021
PubMed
Summary

The nasopharyngeal microbiome, crucial for respiratory health, shifts from infancy to old age. Understanding its dynamics helps prevent infections and manage airway diseases.

Keywords:
microbiomemicrobiotanasopharynxupper respiratory tract

More Related Videos

Murine Oropharyngeal Aspiration Model of Ventilator-associated and Hospital-acquired Bacterial Pneumonia
04:32

Murine Oropharyngeal Aspiration Model of Ventilator-associated and Hospital-acquired Bacterial Pneumonia

Published on: June 28, 2018

12.2K
Purifying the Impure: Sequencing Metagenomes and Metatranscriptomes from Complex Animal-associated Samples
11:23

Purifying the Impure: Sequencing Metagenomes and Metatranscriptomes from Complex Animal-associated Samples

Published on: December 22, 2014

37.5K

Related Experiment Videos

Last Updated: Nov 19, 2025

Assessing the Viability of a Synthetic Bacterial Consortium on the In Vitro Gut Host-microbe Interface
10:24

Assessing the Viability of a Synthetic Bacterial Consortium on the In Vitro Gut Host-microbe Interface

Published on: July 4, 2018

12.0K
Murine Oropharyngeal Aspiration Model of Ventilator-associated and Hospital-acquired Bacterial Pneumonia
04:32

Murine Oropharyngeal Aspiration Model of Ventilator-associated and Hospital-acquired Bacterial Pneumonia

Published on: June 28, 2018

12.2K
Purifying the Impure: Sequencing Metagenomes and Metatranscriptomes from Complex Animal-associated Samples
11:23

Purifying the Impure: Sequencing Metagenomes and Metatranscriptomes from Complex Animal-associated Samples

Published on: December 22, 2014

37.5K

Area of Science:

  • Microbiology
  • Immunology
  • Respiratory Medicine

Background:

  • Human microbiome research has expanded, with growing interest in dysbiosis links to health and disease.
  • The nasopharyngeal microbiome, a key upper respiratory tract niche, is vital for host immunity and pathogen colonization.
  • Nasopharyngeal microbiome dynamics influence respiratory infections and chronic airway diseases.

Purpose of the Study:

  • To review the nasopharyngeal microbiome's development across the lifespan.
  • To examine the role of commensal and pathogenic bacteria in the nasopharynx.
  • To highlight the nasopharyngeal microbiome's importance in maintaining respiratory health.

Main Methods:

  • Literature review focusing on immunological, ecological, and environmental drivers.
  • Analysis of nasopharyngeal microbiome development from neonates to the elderly.
  • Examination of key nasopharyngeal microbial species, including Streptococcus pneumoniae and Staphylococcus aureus.

Main Results:

  • The nasopharyngeal microbiome establishes resilient profiles in neonates.
  • Perturbations in the nasopharyngeal microbiome are associated with pneumonia risk in the elderly.
  • Commensal species like Dolosigranulum and Corynebacterium play beneficial roles.

Conclusions:

  • The nasopharyngeal microbiome is essential for maintaining commensal species equilibrium.
  • Understanding the nasopharyngeal microbiome aids in preventing pathogen outgrowth and supporting host immunity.
  • Future research should focus on the nasopharyngeal microbiome's role in respiratory health and disease.