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Related Concept Videos

Nose and Nasal Cavity01:24

Nose and Nasal Cavity

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The nose is composed of an observable exterior segment (external nose) and an internal segment within the skull known as the nasal cavity (internal nose). The external nose, visible on the face, consists of a framework of bone and hyaline cartilage enveloped in skin and muscle and lined with a mucous membrane. This structure is supported by the frontal bone, nasal bones, and maxillary bone and is supplemented by a cartilaginous framework comprising the septal nasal cartilage, lateral nasal...
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Epistaxis01:30

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Epistaxis, or nosebleeds, occurs when small, swollen blood vessels in the nasal mucous membrane rupture. Typically, the anterior septum is the primary site of occurrence.
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The lateral view of the cranium is dominated by temporal, sphenoid, and ethmoid bones.
The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...
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Suctioning the Nasopharyngeal Airway01:29

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Nasopharyngeal suctioning is a procedure to remove secretions from the upper part of the respiratory tract that the patient cannot clear independently. It helps maintain airway patency and prevents complications such as aspiration pneumonia.
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The upper respiratory tract plays a vital role in the respiratory system, comprising several structures that facilitate air intake and prepare air for the lungs. It also serves as the first line of defense against pathogens and particles. This tract includes the nose and nasal cavity, the oral cavity, the paranasal sinuses, and the pharynx, each with specific functions and features.
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Updated: Nov 18, 2025

Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
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Sine Qua Non: Sinonasal Inverted Papilloma.

Frederic C Jewett1, Michael J Coulter2, Brenda L Nelson3

  • 1Department of Pathology, Naval Medical Center San Diego, 34800 Bob Wilson Drive, San Diego, CA, 92134-5000, USA. frederic.c.jewett.mil@mail.mil.

Head and Neck Pathology
|February 5, 2021
PubMed
Summary
This summary is machine-generated.

Inverted papilloma (IP) of the sinonasal tract, though benign, can cause destruction and recur. Accurate differentiation from similar conditions is vital for patient risk assessment and monitoring.

Area of Science:

  • Otolaryngology
  • Pathology
  • Oncology

Background:

  • Inverted papilloma (IP) is a common sinonasal tumor originating from squamous epithelium.
Keywords:
HPVHPV-mediated squamous cell carcinomaInverted papillomaOncocytic papillomaSchneiderianSinonasal papilloma

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  • Despite being histologically benign, IP exhibits aggressive local behavior, including bone destruction and high recurrence rates.
  • A significant concern is the potential for malignant transformation, necessitating precise diagnosis.