Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Larynx01:21

Larynx

3.7K
The human larynx, often referred to as the voice box, is an intricate organ located in the neck. It serves as a pathway for air to enter the lungs during respiration and is an essential component of voice production.
Anatomy of the Larynx
The larynx consists of various components, including cartilage, muscles, and vocal cords. Its structure includes three large unpaired cartilages—the thyroid, cricoid, and epiglottis—and three smaller paired cartilages—the arytenoids,...
3.7K
Drugs for Peptic Ulcer Disease: Sucralfate as Mucosal Protective Agents01:24

Drugs for Peptic Ulcer Disease: Sucralfate as Mucosal Protective Agents

1.2K
In the intricate landscape of the gastric lumen, excessive acid secretion disrupts the natural defense mechanisms, weakening the mucus-bicarbonate barrier. This vulnerability allows pepsin to infiltrate epithelial cells, digesting mucosal proteins and triggering erosion, leading to ulcer formation.
In this scenario, mucosal protective agents like sucralfate play an essential role. Sucralfate, a complex of sulfated sucrose and aluminum hydroxide, demonstrates its usefulness in acidic conditions,...
1.2K
Peptic Ulcer Disease I: Introduction01:30

Peptic Ulcer Disease I: Introduction

660
Peptic Ulcer Disease (PUD) is characterized by mucosal excavation in the esophagus, stomach, pylorus, or duodenum. It can manifest as acute or chronic based on the extent and duration of mucosal involvement.
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
660
Peptic Ulcer Disease V: Surgical Management and Nursing Care01:25

Peptic Ulcer Disease V: Surgical Management and Nursing Care

712
Surgical management and nursing care are crucial in treating Peptic Ulcer Disease (PUD). Here is an organized and enhanced overview of the surgical interventions and the associated nursing care for PUD:
Surgical Interventions for Peptic Ulcer Disease
712
Esophageal Perforation-II: Clinical Manifestations and Management01:28

Esophageal Perforation-II: Clinical Manifestations and Management

357
Esophageal perforations manifest in various clinical forms, influenced by factors such as the perforation's cause and location (cervical, intrathoracic, or intra-abdominal), the extent of contamination, and potential injury to adjacent mediastinal structures. The timing between the perforation occurrence and treatment initiation also affects the clinical presentation.
Clinical Manifestations:
357
Peptic Ulcer Disease II: Pathophysiology01:28

Peptic Ulcer Disease II: Pathophysiology

1.7K
Peptic Ulcer Disease (PUD) is characterized by the development of ulcers in the stomach or duodenal mucosa. Its pathophysiology is complex, involving a balance between damaging and protective elements.
Damaging agents such as Helicobacter pylori, gastric acid, pepsin, and nonsteroidal anti-inflammatory drugs (NSAIDs) can weaken the mucosal defense, allowing hydrogen ions to infiltrate back and harm epithelial cells.
1.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

HN-CLEAR: Head and Neck Consensus Language for Ease and Reproducibility, a Multidisciplinary Consensus Mechanism for Head and Neck Pathology.

Head and neck pathology·2023
Same author

Sine Qua Non: Oncocytoma.

Head and neck pathology·2022
Same author

Sine Qua Non: Dentigerous Cyst.

Head and neck pathology·2021
Same author

Sine Qua Non: Sinonasal Inverted Papilloma.

Head and neck pathology·2021
Same author

Lymphangioma of the Dorsal Tongue.

Head and neck pathology·2019
Same author

Benign Fibro-Osseous Lesions of the Head and Neck.

Head and neck pathology·2019
Same journal

Oral Diagnosis of Lepromatous Leprosy in a Hyperendemic Region of Brazil.

Head and neck pathology·2026
Same journal

NUT Carcinoma Arising in Stensen's Duct: First Reported Case and Literature Review.

Head and neck pathology·2026
Same journal

FGFR3::TACC3 Fusion and NOTCH1 Loss-of-Function in a Case of HPV-Associated Sinonasal Squamous Cell Carcinoma: Diagnostic Challenge and Implications for Targeted Therapy.

Head and neck pathology·2026
Same journal

Oncocytic Intraductal Carcinoma of the Parotid Gland with STRN::ALK Fusion.

Head and neck pathology·2026
Same journal

Pitfalls in Bone and Soft Tissue Pathology of the Head and Neck: Primary Intraosseous Rhabdomyosarcoma/FUS::TFCP2-Rearranged Spindle Cell Rhabdomyosarcoma and Transdifferentiated/Dedifferentiated/Undifferentiated Melanoma.

Head and neck pathology·2026
Same journal

Artificial Intelligence-Assisted Histopathologic Diagnosis and Grading of Oral Epithelial Dysplasia: A Systematic Review and Functional Meta-synthesis.

Head and neck pathology·2026
See all related articles

Related Experiment Video

Updated: Dec 22, 2025

Learning Modern Laryngeal Surgery in a Dissection Laboratory
07:30

Learning Modern Laryngeal Surgery in a Dissection Laboratory

Published on: March 18, 2020

8.6K

Laryngeal Contact Ulcer.

Benjamin G Barrena1, Tanner M Miller2, Brenda L Nelson2

  • 1Department of Anatomic Pathology, Naval Medical Center San Diego, 34800 Bob Wilson Drive, San Diego, CA, 92134-5000, USA. benjamin.g.barrena.mil@mail.mil.

Head and Neck Pathology
|May 9, 2020
PubMed
Summary
This summary is machine-generated.

A large pedunculated mass in the larynx, diagnosed as a laryngeal contact ulcer, caused voice and swallowing issues. Treatment with laser ablation and corticosteroid injection successfully resolved symptoms.

Keywords:
Contact ulcerLaryngeal contact ulcerLaryngeal pyogenic granulomaLarynxPyogenic granulomaVocal process granuloma

More Related Videos

Identification and Protection of the Recurrent Laryngeal Nerve during Transoral Robotic Thyroidectomy
05:25

Identification and Protection of the Recurrent Laryngeal Nerve during Transoral Robotic Thyroidectomy

Published on: October 24, 2025

233
Minimally Invasive Murine Laryngoscopy for Close-Up Imaging of Laryngeal Motion During Breathing and Swallowing
07:22

Minimally Invasive Murine Laryngoscopy for Close-Up Imaging of Laryngeal Motion During Breathing and Swallowing

Published on: December 1, 2023

859

Related Experiment Videos

Last Updated: Dec 22, 2025

Learning Modern Laryngeal Surgery in a Dissection Laboratory
07:30

Learning Modern Laryngeal Surgery in a Dissection Laboratory

Published on: March 18, 2020

8.6K
Identification and Protection of the Recurrent Laryngeal Nerve during Transoral Robotic Thyroidectomy
05:25

Identification and Protection of the Recurrent Laryngeal Nerve during Transoral Robotic Thyroidectomy

Published on: October 24, 2025

233
Minimally Invasive Murine Laryngoscopy for Close-Up Imaging of Laryngeal Motion During Breathing and Swallowing
07:22

Minimally Invasive Murine Laryngoscopy for Close-Up Imaging of Laryngeal Motion During Breathing and Swallowing

Published on: December 1, 2023

859

Area of Science:

  • Otolaryngology
  • Laryngology
  • Pathology

Background:

  • Globus sensation, throat clearing, and voice changes are common symptoms requiring investigation.
  • Laryngeal masses can significantly impact vocal function and swallowing.
  • Contact ulcers are a recognized laryngeal pathology often associated with voice misuse or reflux.

Observation:

  • A 47-year-old man presented with a 6-month history of globus sensation, throat clearing, and subjective voice lowering.
  • Flexible nasolaryngoscopy revealed a large pedunculated mass on the left arytenoid vocal process.
  • Initial conservative management with anti-reflux therapy and speech therapy yielded minimal improvement.

Findings:

  • Suspension microlaryngoscopy with biopsy confirmed a laryngeal contact ulcer.
  • Histopathology showed mucosal ulceration, fibrinoid necrosis, inflammatory infiltrate, and granulation tissue.
  • The mass was successfully treated with potassium titanyl phosphate (KTP) laser ablation and corticosteroid microinjection.

Implications:

  • This case highlights the diagnostic process for laryngeal masses presenting with voice and swallowing complaints.
  • Effective treatment options for laryngeal contact ulcers include minimally invasive procedures like laser ablation.
  • Successful management can lead to significant improvement in voice quality, cough, and dysphagia.