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A case of Trueperella pyogenes causing prosthetic joint infection
Tariq Azamgarhi1, Simon Warren2
1Pharmacy Department, Royal National Orthopaedic Hospital NHS Trust, Brockley Hill, Stanmore, HA7 4LP, UK.
Journal of Bone and Joint Infection
|February 8, 2021
Summary
We report the first prosthetic joint infection caused by Trueperella pyogenes, an uncommon bacterium in humans. The patient recovered after surgery and a 12-week course of antibiotics.
Area of Science:
- Infectious Diseases
- Orthopedic Surgery
- Microbiology
Background:
- Prosthetic joint infections (PJIs) are serious complications following joint replacement surgery.
- Trueperella pyogenes is primarily an animal pathogen with rare documented human infections.
- Limited information exists on T. pyogenes as a cause of PJI.
Observation:
- A patient presented with a prosthetic joint infection.
- Cultures identified Trueperella pyogenes as the causative agent.
Findings:
- This is the first documented case of PJI caused by Trueperella pyogenes.
- Successful treatment was achieved with single-stage exchange arthroplasty.
- A 12-week course of rifampicin and moxifloxacin was administered.
Implications:
- Highlights the potential for Trueperella pyogenes to cause human infections, including PJIs.
- Demonstrates the efficacy of surgical intervention and targeted antibiotic therapy for this rare pathogen.
- Informs clinical awareness and management strategies for unusual PJI etiologies.
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