Related Experiment Video
Updated: Nov 18, 2025

Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index
Published on: January 8, 2020
Clustering and Healthcare Costs With Multiple Chronic Conditions in a US Study.
Cother Hajat1, Yakir Siegal2, Amalia Adler-Waxman3
1Public Health Institute, United Arab Emirates (UAE) University, Al Ain, United Arab Emirates.
Multiple chronic conditions (MCCs) affect nearly half of insured US patients, significantly increasing healthcare costs. A multi-condition approach is recommended for health system redesign to manage these complex patient needs.
Area of Science:
- Health Economics
- Public Health
- Chronic Disease Management
Background:
- Multiple chronic conditions (MCCs) represent a significant burden on healthcare systems.
- Understanding the cost drivers and common condition clusters is crucial for effective resource allocation.
Purpose of the Study:
- To investigate healthcare costs and their contributors for patients with MCCs.
- To identify common clusters of chronic conditions and their impact on healthcare utilization and spending.
Main Methods:
- Cross-sectional analysis of US financial claims data (Medicare, Medicaid, Commercial) from 2015.
- Inclusion of 1,878,951 patients, weighted to represent the US population.
- Unsupervised (k-means) clustering analysis to identify condition groups and their associated costs.
Main Results:
- Nearly half (49.6%) of patients had MCCs, with mean annual spending of $12,601.
- Spending increased significantly with the number of conditions, particularly for inpatient and outpatient services.
- Common clusters included metabolic syndrome, age-related diseases, renal failure, respiratory disorders, cardiovascular disease (CVD), cancers, mental health conditions, and HIV/AIDS.
Conclusions:
- MCCs are prevalent and associated with increased healthcare utilization and costs.
- Findings support a health system redesign focused on managing clusters of chronic conditions.
- Cost-containment strategies for MCCs are essential for sustainable healthcare.
Related Concept Videos
Methods of Documentation VI: Case Management Model
For example, a patient with a chronic...
Issues And Trends In Healthcare Delivery System
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
Methods Of Healthcare Delivery System
Managed Care System:
The managed care system is designed to control the cost while maintaining the quality of care. The patient's care from admission to discharge is planned by the primary care provider or the case manager, also known as the gatekeeper. In a managed care system, the number of care providers is...
Factors Affecting Illness
For instance, risk factors are connected to illness,...
Cluster Sampling Method
To choose a cluster sample, divide the population into clusters (groups) and then randomly select some of the clusters. All the members from these clusters are in the cluster sample. For example, if you randomly sample four departments from your...
Traditional Level Of Health Care System
The preventive healthcare service includes tests for screening. Preventive health care services include identifying and reducing disease risk...

