Related Experiment Video
Updated: Nov 18, 2025

Establishing a Device for Sleep Deprivation in Mice
Published on: September 22, 2023
Sleep Disorders in dogs: A Pathophysiological and Clinical Review
Alejandra Mondino1, Luis Delucchi2, Adam Moeser3
1Department of Anesthesiology, University of Michigan, Ann Arbor, MI, USA; Laboratorio de Neurobiología del Sueño, Departamento de Fisiología, Facultad de Medicina, Universidad de la República, Montevideo, Uruguay; Unidad de Neurología, Departamento de Patología y Clínica de Pequeños Animales, Universidad de la República, Montevideo, Uruguay.
Abstract:
Sleep is a fundamental process in mammals, including domestic dogs. Disturbances in sleep affect physiological functions like cognitive and physical performance, immune response, pain sensation and increase the risk of diseases. In dogs, sleep can be affected by several conditions, with narcolepsy, REM sleep behavior disorder and sleep breathing disorders being the most frequent causes. Furthermore, sleep disturbances can be a symptom of other primary diseases where they can contribute to the worsening of clinical signs. This review describes reciprocally interacting sleep and wakefulness promoting systems and how their dysfunction can explain the pathophysiological mechanisms of sleep disorders. Additionally, this work discusses the clinical characteristics, diagnostic tools and available treatments for these disorders while highlighting areas in where further studies are needed so as to improve their treatment and prevention.
More Related Videos
Related Concept Videos
Narcolepsy
Sleep-Wake Cycles
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
Substance Use Disorders Affecting Sleep
Understanding the concepts of physical dependence,...
Understanding Sleep
The circadian rhythm, a nearly 24-hour cycle, is deeply influenced by environmental light cues. Light exposure directly affects the hypothalamus, which in turn regulates...
REM Sleep Behavior Disorder
RBD is significantly associated with...
Insufficient Sleep and Sleep Deprivation
Sleep deprivation is a more severe form of sleep loss...

