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Positron Emission Tomography

Positron Emission Tomography

Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
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Related Experiment Video

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Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

Published on: June 7, 2015

Proton Therapy for Mandibula Plate Phantom.

Güler Burcu Senirkentli¹, Fatih Ekinci², Erkan Bostanci³

¹Department of Pediatric Dentistry, Baskent University, Ankara 06810, Turkey.

Healthcare (Basel, Switzerland)

|February 9, 2021

Summary

This summary is machine-generated.

Proton therapy dose rates were calculated for mandible tumors, optimizing treatment and protecting surrounding tissues. Findings guide energy selection to minimize radiation damage during mandible cancer treatment.

Keywords:

biomaterials bragg peak dental tumour mandible plate phantom paediatric dentistry proton treatment

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Published on: March 24, 2022

Area of Science:

Medical Physics
Radiation Oncology
Biomedical Engineering

Background:

Proton therapy offers precise radiation delivery, crucial for head and neck cancers.
Mandibular tumors require careful treatment planning to spare critical structures.
Optimizing proton energy is key to maximizing tumor dose while minimizing collateral damage.

Purpose of the Study:

To calculate optimal proton therapy dose rates for mandible tumors.
To protect surrounding soft and hard tissues from radiation.
To prevent radiation-induced complications in mandible cancer treatment.

Main Methods:

Modeled mandibular tooth plate phantoms (molar and premolar areas).
Utilized Monte Carlo simulations to compute proton Bragg curves, lateral straggle/range, and recoil values.
Investigated the impact of jawbone layer density, type, and thickness on proton behavior.

Main Results:

Increased cortical bone thickness decreased Bragg peak position (0.47-3.3%).
More layers led to a reduced Bragg peak position.
Higher proton energy decreased the amplitude and effect of the second peak on Bragg peak position.

Conclusions:

Findings provide guidance for selecting appropriate proton energy levels.
Enables effective treatment of mandibular tumors with reduced damage to surrounding tissues.
Aims to improve patient outcomes by minimizing radiation side effects.