Related Experiment Video
Updated: Nov 18, 2025
Synthesis and Characterization of Placental Chondroitin Sulfate A plCSA-Targeting Lipid-Polymer Nanoparticles
Published on: September 18, 2018
Chitosan - A Potential Polymer to Prepare Anticancer Drug Delivery Systems: Patent Review
Priyanka Kriplani1, Kumar Guarve1
1Guru Gobind Singh College of Pharmacy, Yamuna Nagar 135001, Haryana, India.
Background:
Polymers are used in drug delivery systems to encapsulate and release the drug. Natural polymers have the advantages of biodegradability, biocompatibility, and recognizable biological moieties that maintain cellular functions as compared to synthetic polymers. Chitosan is a natural polycationic linear polysaccharide that originates from chitin. Its easy modification, release rate of drug, ability to cross-link with other polymers, gelling ability, immunostimulation, bioadhesion, biocompatibility, and biodegradability has increased its application in various drug delivery systems.
Objective:
The objective of the present study is to overview the recent patents of the application of chitosan in various drug delivery systems and their use in the prevention of cancer and other ailments.
Methods:
In this review, the patent application of chitosan in various drug delivery systems employed to cure mainly cancer has been covered with particular emphasis on their scientific impact and novelty.
Results:
Chitosan has proved its potential as a polymer to control and target the drug at the site of action.
Conclusion:
The potential of chitosan and its derivatives to deliver and target the drug may open new avenues for therapeutic interventions in different tumors.
Related Concept Videos
01:05Bioavailability Enhancement: Drug Stability Enhancement and GI Retention
02:57Targeted Cancer Therapies
There are several types of targeted therapies against...
02:49Cancer Therapies
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...