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[Therapy of rheumatic fever].
Summary
Prompt treatment of rheumatic fever, a secondary condition to streptococcal infection, involves penicillin G and anti-inflammatory drugs like prednisolone. Long-term penicillin prophylaxis is crucial for preventing recurrence, especially in children.
Area of Science:
- Rheumatology
- Infectious Diseases
- Pediatrics
Context:
- Rheumatic fever is a secondary sequela of streptococcal infections.
- Prompt diagnosis and treatment are critical for managing rheumatic fever.
- Mesenchymal tissue inflammation is a key pathological feature.
Purpose:
- To outline the immediate and long-term treatment strategies for rheumatic fever.
- To detail pharmacologic interventions for streptococcal infection and its sequelae.
- To establish guidelines for prophylaxis and rehabilitation.
Summary:
- Immediate treatment involves penicillin G for streptococcal infection and anti-inflammatory agents (prednisolone, aminophenazone, salicylic acid) for inflammation, with preferences for children.
- Recurrence prevention (prophylaxis) utilizes benzathine penicillin G up to age five, with alternatives like V-tablopen, erythromycin, or sulfaclomide.
- Hospitalization continues until inflammation subsides and fever-free for four weeks, followed by gradual rehabilitation.
Impact:
- Ensures effective management of acute rheumatic fever episodes.
- Reduces the incidence of rheumatic heart disease through sustained prophylaxis.
- Improves patient outcomes via structured treatment and rehabilitation protocols.