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[Origin of plague moderate phages of serotype 2]
Abstract:
Results of study of the negative colonies morphology, the structure of corpuscles, antigenic properties, specificity, and the action range permitted to refer the phages obtained from 18 E. coli strain, 1 plaque strain, and 1 pseudotoberculosis bacillus strain to the same group and to identify them with plague phages of serological type 2. Isolation of the same phage type from different bacterial species permits to regard them as "polyhostal" ones. E. coli should be considered as the main carrier of phages belonging to serological type 2. It is suggested that phages existing on microbes belonging to different species should be called "polyhostal".
Insights
Researchers identified plague phages of serological type 2 from E. coli and other bacteria. These "polyhostal" phages, primarily carried by E. coli, can infect multiple bacterial species.
Area of Science:
- Microbiology
- Virology
- Bacteriology
Background:
- Bacteriophages are viruses that infect bacteria.
- Escherichia coli (E. coli) and Yersinia pestis are significant bacterial species.
- Serological typing is crucial for classifying bacterial strains and phages.
Purpose of the Study:
- To characterize phages isolated from E. coli and other bacterial species.
- To determine if these phages are related to plague phages.
- To investigate the host range and carrier status of these phages.
Main Methods:
- Analysis of negative colony morphology.
- Examination of corpuscle structure.
- Assessment of antigenic properties and specificity.
- Determination of the phage action range.
- Serological identification of phages.
Main Results:
- Phages from 18 E. coli strains, 1 plaque strain, and 1 Yersinia pseudotuberculosis strain were grouped together.
- These phages were identified as plague phages of serological type 2.
- The isolation of the same phage type from different bacterial species suggests they are "polyhostal" (infecting multiple hosts).
- E. coli was identified as the primary carrier of serological type 2 phages.
Conclusions:
- Phages isolated from E. coli and other species belong to plague phage serological type 2.
- The term "polyhostal" is proposed for phages found across different bacterial species.
- E. coli plays a key role in the dissemination of these specific phages.