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Updated: Nov 17, 2025

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Generation of Tissue Spheroids via a 3D Printed Stamp-Like Device
Published on: October 6, 2022
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Discovering the Latest Scientific Pathways on Tissue Spheroids: Opportunities to Innovate
Marisela Rodriguez-Salvador1, Baruc Emet Perez-Benitez1, Karen Marcela Padilla-Aguirre1
1Tecnologico de Monterrey, Escuela de Ingenieria y Ciencias, CP 64849, Monterrey, N.L., Mexico.
International Journal of Bioprinting
|February 15, 2021
Summary
Tissue spheroids, 3D cell models, offer innovative solutions in regenerative medicine and drug testing. This study analyzes research trends to guide future health industry applications.
Area of Science:
- Biomedical Engineering
- Regenerative Medicine
- Drug Discovery
Background:
- Tissue spheroids are 3D cell models mimicking human tissue complexity.
- They hold potential for tissue engineering and pharmaceutical research.
- Understanding research dynamics is crucial for innovation in the health industry.
Purpose of the Study:
- To conduct a scientometric analysis of tissue spheroid research.
- To identify key applications and research trends in the field.
- To inform strategic decisions for adopting new health technologies.
Main Methods:
- Scientometric analysis of 868 publications from Scopus and Web of Science (2000-2019).
- Competitive Technology Intelligence methodology.
- Cluster analysis for collaboration network identification.
Main Results:
- Four main application categories for tissue spheroids were identified.
- Key research areas, leading countries, institutions, and authors were mapped.
- Collaboration networks between researchers and institutions were visualized.
Conclusions:
- The study provides comprehensive insights into tissue spheroid applications and research landscape.
- Findings can guide decision-making for integrating advanced technologies in healthcare.
- Identified trends support the strategic development of regenerative medicine and drug testing platforms.

