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Case for diagnosis. Atypical Grover's disease.

Pablo Vargas-Mora1, Diego Orlandi1, Irene Araya1

  • 1Department of Dermatology, Faculty of Medicine, Universidad de Chile, Santiago, Chile.

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Summary

This case study describes a rare presentation of Grover's disease (transient aphornic eruption) in a 55-year-old male. The patient exhibited atypical chronic symptoms including facial involvement and pityriasis rubra pilaris-like lesions.

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AcantholysisAtypicalGrover’s diseaseTransient acantholytic dermatosis

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Area of Science:

  • Dermatology
  • Rare Diseases
  • Clinical Case Studies

Background:

  • Grover's disease, also known as transient aphornic eruption, is an uncommon acquired skin condition of unknown etiology.
  • It typically presents as transient erythematous papules on the upper trunk.

Observation:

  • A 55-year-old male presented with an eight-month history of skin lesions.
  • Lesions included erythematous papules and plaques with distinct areas of unaffected skin.
  • Affected areas were the trunk, upper extremities, neck, and face.

Findings:

  • The patient's presentation was atypical for Grover's disease.
  • Features included facial involvement and a chronic disease course.
  • Lesions also exhibited characteristics resembling pityriasis rubra pilaris.

Implications:

  • This case highlights the variable clinical spectrum of Grover's disease.
  • It underscores the importance of considering atypical presentations in dermatological diagnosis.
  • Further research may elucidate the pathogenesis of chronic and extratruncal Grover's disease.