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Calcium phosphate-coated porous titanium implants for enhanced skeletal fixation
D P Rivero1, J Fox, A K Skipor
1Department of Orthopedic Surgery, Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois 60612.
Journal of Biomedical Materials Research
|March 1, 1988
Summary
Calcium phosphate-coated titanium implants enhanced bone fixation strength by 24% at four weeks in dogs. This study investigated porous titanium fiber implants for cementless skeletal fixation.
Area of Science:
- Biomaterials Science
- Orthopedic Surgery
- Tissue Engineering
Background:
- Porous titanium fiber implants are used for cementless skeletal fixation.
- Bone ingrowth is crucial for stable implant integration.
- Calcium phosphate coatings are explored to enhance osseointegration.
Purpose of the Study:
- To evaluate the effect of calcium phosphate coating on the biomechanical strength and bone ingrowth of porous titanium fiber implants.
- To assess the osteoconductive properties of the coating.
Main Methods:
- Porous titanium fiber implants were coated with calcium phosphate using plasma flame-spray.
- Coated and control implants were inserted into dog humeri and olecranons.
- Biomechanical shear strength and histological bone ingrowth were evaluated at 1, 2, 4, and 6 weeks.
Main Results:
- Calcium phosphate-coated implants showed a 24% greater mean shear strength at 4 weeks compared to controls (P < .01).
- No significant difference in fixation strength was observed at other time points.
- Bone formation in direct contact with the coating confirmed osteoconductivity.
- No significant increase in bone ingrowth volume was found for coated implants.
Conclusions:
- Calcium phosphate coating enhances the early biomechanical fixation strength of porous titanium implants.
- The coating demonstrates osteoconductive properties, facilitating direct bone contact.
- Further research may be needed to optimize coating for increased bone ingrowth volume.