Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Auditory brainstem response in obstructive sleep apnea.

S J Wetmore1, C Henderson, N W Doshier

  • 1Department of Otolaryngology and Maxillofacial Surgery, University of Arkansas for Medical Sciences, Little Rock 72205.

The Laryngoscope
|May 1, 1988
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Measurements of <math></math> production cross sections and constraints on anomalous triple gauge couplings at <math> </math>.

The European physical journal. C, Particles and fields·2021
Same author

Search for dark matter produced in association with a leptonically decaying <math></math> boson in proton-proton collisions at <math> </math>.

The European physical journal. C, Particles and fields·2021
Same author

Search for top squark pair production using dilepton final states in <math></math> collision data collected at <math> </math>.

The European physical journal. C, Particles and fields·2021
Same author

Mental health and caregiving experiences of family carers supporting people with psychosis.

Epidemiology and psychiatric sciences·2021
Same author

Measurement of single-diffractive dijet production in proton-proton collisions at <math> </math> with the CMS and TOTEM experiments.

The European physical journal. C, Particles and fields·2020
Same author

Evidence for Top Quark Production in Nucleus-Nucleus Collisions.

Physical review letters·2020
Same journal

Discrimination of Pairs of Chemosensory Stimuli in Relation to Respiration.

The Laryngoscope·2026
Same journal

What Safety Precautions Are Recommended When Lasering in the Airway?

The Laryngoscope·2026
Same journal

Success of Anterior Ethmoidal Artery Flaps for Nasal Septal Perforation Repair: A Systematic Review.

The Laryngoscope·2026
Same journal

Laryngeal IgG4-Related Disease: A Systematic Review of Clinical Features and Management.

The Laryngoscope·2026
Same journal

Elevated BMI Is Not Associated With Adverse Outcomes in Open Airway Reconstruction.

The Laryngoscope·2026
Same journal

What is the Most Effective Treatment Approach for Vocal Fold Granuloma?

The Laryngoscope·2026
See all related articles

Obstructive sleep apnea (OSA) may cause brainstem dysfunction, indicated by prolonged auditory brainstem response (ABR) latencies. These ABR abnormalities may resolve after OSA treatment.

Area of Science:

  • Neuroscience
  • Sleep Medicine
  • Audiology

Background:

  • Auditory brainstem response (ABR) is utilized to investigate brainstem involvement in obstructive sleep apnea (OSA) pathophysiology.
  • Previous studies on ABR in OSA patients have yielded inconsistent findings.
  • The impact of pathological sleepiness in OSA on brainstem function requires further elucidation.

Purpose of the Study:

  • To assess auditory brainstem response (ABR) characteristics in patients with obstructive sleep apnea (OSA) before and after treatment.
  • To investigate the potential correlation between OSA severity and ABR abnormalities.
  • To determine if rapid-rate auditory stimuli can reveal differences in ABR between OSA patients and controls.

Main Methods:

  • Auditory brainstem response (ABR) was recorded in 27 preoperative OSA patients and 17 healthy controls using click stimuli at slow (11.7 Hz) and fast (57.7 Hz) rates.

Related Experiment Videos

  • ABR was re-evaluated postoperatively in 18 OSA patients.
  • Statistical analysis was performed to compare ABR parameters between groups and conditions.

    • Main Results:

    • No significant differences in ABR were observed between preoperative OSA patients and the control group.
    • Preoperative ABR recordings showed statistically significant prolonged latencies for wave III and interpeak latency (IPL) I-III compared to postoperative recordings (p < 0.01).
    • Fast-rate ABR testing did not provide additional diagnostic value.

    Conclusions:

    • While normal sleep does not induce ABR abnormalities, the excessive sleepiness associated with OSA may lead to measurable brainstem dysfunction.
    • Prolonged ABR latencies observed in OSA patients may indicate reversible brainstem abnormalities.
    • Treatment of OSA may lead to the resolution of these auditory pathway alterations.