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Published on: May 21, 2019
Photocatalyst- and Transition-Metal-Free Visible-Light-Promoted Intramolecular C(sp2)-S Formation
Hao Wang1, Qi Wu1, Jian-Dong Zhang1
1College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123, China.
Abstract:
A photocatalyst- and transition-metal-free visible-light-induced cyclization of ortho-halothiobenzanilides has been developed. Upon irradiation with visible light, substrates undergo dehalogenative cyclization to 2-aryl benzothiazoles with high efficiency and selectivity. This photocyclization exhibits a high tolerance to various functional groups, is applicable for the synthesis of 2-alkyl benzothiazoles, and is easy to set up for gram-scale reaction.
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