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Continuous flow fast atom bombardment liquid chromatography/mass spectrometry: studies involving conventional bore
D E Games1, S Pleasance, E D Ramsey
1Department of Chemistry, University College, Cardiff, UK.
Biomedical & Environmental Mass Spectrometry
|February 1, 1988
Abstract:
A conventional bore liquid chromatograph has been interfaced to quadrupole and magnetic sector mass spectrometers configured for fast atom bombardment ionization via a continuous flow FAB probe. It is shown that post-column addition of FAB matrix and in-line ultraviolet detection facilities do not significantly compromise chromatographic integrity and that high quality mass spectra are obtainable from such FAB LC/MS studies.