Synthesis and defect engineering of molybdenum oxides and their SERS applications

Surface-enhanced Raman scattering (SERS) spectroscopy has been developed into a cross-disciplinary analytical technology through exploring various materials' Raman vibrational modes with ultra-high sensitivity and specificity. Although conventional noble-metal based SERS substrates have achieved great success, oxide-semiconductor-based SERS substrates are attracting researchers' intensive interest due to their merits of facile fabrication, high uniformity and tunable SERS characteristics. Among all the SERS active oxide semiconductors, molybdenum oxides (MoO_x) possess exceptional advantages of high Raman enhancement factor, environmental stability, recyclable detection, etc. More interestingly, the SERS effect of the MoO_x SERS substrates may involve both the electromagnetic enhancement mechanism and the chemical enhancement mechanism, which is determined by the stoichiometry and morphology of the material. Therefore, the focus of this review will be on two critical points: (1) synthesis and material engineering methods of the functional MoO_x material and (2) MoO_x SERS mechanism and performance evaluation. First, we review recent works on the MoO_x preparation and material property tuning approaches. Second, the SERS mechanism and performance of various MoO_x substrates are surveyed. In particular, the performance uniformity, enhancement factor and recyclability are evaluated. In the end, we discuss several challenges and open questions related to further promoting the MoO_x as the SERS substrate for monitoring extremely low trace molecules and the theory for better understanding of the SERS enhancement mechanism.