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Updated: Nov 14, 2025

Synthesis of Core-shell Lanthanide-doped Upconversion Nanocrystals for Cellular Applications

Synthesis of Core-shell Lanthanide-doped Upconversion Nanocrystals for Cellular Applications

Published on: November 10, 2017

Exploring Heterostructured Upconversion Nanoparticles: From Rational Engineering to Diverse Applications.

Yi Zhang^1,2, Xiaohui Zhu¹, Yong Zhang²

¹School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, China.

|March 10, 2021

Summary

This summary is machine-generated.

Heterostructured upconversion nanoparticles (UCNPs) combine UCNPs with other materials, offering enhanced properties for bioimaging, biodetection, and phototherapy. This review covers their construction, synthesis, and biomedical applications.

Keywords:

bioimaging biosensing deep tissue penetration heterostructure near-infrared light phototherapy rare earth upconversion nanoparticles

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Area of Science:

Materials Science
Nanotechnology
Biomedical Engineering

Background:

Upconversion nanoparticles (UCNPs) convert low-energy photons to high-energy emissions.
Heterostructured UCNPs integrate UCNPs with other functional materials (metals, semiconductors, polymers).
These multicomponent nanomaterials exhibit tunable physicochemical properties influenced by composition and morphology.

Purpose of the Study:

To review recent advancements in heterostructured UCNPs.
To summarize construction strategies, synthetic approaches, and types of heterostructured UCNPs.
To highlight trends and challenges in their biomedical applications.

Main Methods:

Literature review of heterostructured UCNP research.
Analysis of construction strategies and synthesis methods.
Summary of applications in bioimaging, biodetection, and phototherapy.

Main Results:

Heterostructured UCNPs offer bifunctional or multifunctional properties.
Diverse construction strategies and synthetic routes are available.
Significant potential for expanded biomedical applications is demonstrated.

Conclusions:

Heterostructured UCNPs represent a promising class of nanomaterials.
Further research is needed to address challenges in their development and application.
Potential solutions and future directions are discussed.